Chronic / Postoperative Knee Pain

Targeted Cryoneurolysis for Persistent Knee Pain After Injury or Surgery

What Is It?

Persistent knee pain following surgery, trauma, or arthritis can result from overactive or damaged sensory nerves within the knee joint. Even after a successful knee replacement or arthroscopic procedure, many patients report lingering pain that limits their mobility, activity level, and quality of life.

In many cases, this pain is not caused by joint instability or mechanical failure — but rather by irritation or entrapment of the genicular nerves, which transmit pain from the knee to the brain.

Common symptoms include:

  • Persistent knee pain long after recovery from surgery or injury
  • Aching or burning pain with standing, walking, or climbing stairs
  • Tenderness around the front, side, or back of the knee
  • Increased sensitivity to pressure or temperature
  • Limited mobility due to pain, even with good joint healing

Common Causes

Cryoneurolysis may benefit knee pain resulting from:

  • Total knee replacement (TKR) or revision procedures
  • Post-arthroscopy or ligament repair surgery
  • Genicular nerve irritation or entrapment
  • Chronic inflammation or arthritis-related nerve sensitization
  • Residual pain with no clear structural cause

How Cryoneurolysis Helps

Barcelona Cryo Center performs ultrasound-guided cryoneurolysis to treat the genicular nerves — the primary sensory nerves responsible for knee pain. By applying precisely controlled cold therapy, these nerves are temporarily deactivated, stopping abnormal pain signals while preserving strength and joint function.

This approach is especially valuable for patients who have already tried medications, injections, or even surgery without sustained relief. Cryoneurolysis can also be performed while patients are waiting for surgery, providing meaningful pain relief and improved quality of life during the preoperative period.

Key Benefits:

  • Minimally invasive: No incisions or general anesthesia
  • Outpatient procedure: Done in the clinic with minimal downtime
  • Safe and repeatable: Relief may last several months per treatment
  • Joint-preserving: Targets nerves without affecting joint mechanics
  • Drug-free option: Reduces reliance on opioids or NSAIDs

Ideal Candidates

You may be a candidate for cryoneurolysis if you:

  • Have ongoing pain after knee surgery or injury
  • Experience sharp, aching, or burning pain around the knee
  • Have exhausted other conservative treatments
  • Want a nonsurgical, precision-based approach to relief

Step Toward Comfort and Mobility

Chronic knee pain can keep you from walking, working, and living the life you want. Cryoneurolysis offers a safe, targeted solution — helping you move with greater ease and less pain.

Book your consultation with Barcelona Cryo Center today.

Lower Extremity Conditions We Treat

We use cryoneurolysis to help patients manage a range of nerve-related pain conditions in the lower limbs:

Meralgia Paresthetica

Burning, tingling, or numbness in the outer thigh due to compression of the lateral femoral cutaneous nerve.

Chronic / Postoperative Hip Pain

Ongoing hip pain following surgery or due to arthritis, often involving the lateral femoral cutaneous or superior gluteal nerves.

Chronic / Postoperative Knee Pain

Pain after knee replacement or injury, commonly linked to genicular nerve irritation.

Chronic / Postoperative Foot Pain

Pain following foot surgery, trauma, or related to plantar fasciitis or nerve entrapment.

Morton’s Neuroma

Sharp or burning pain between the toes due to thickened nerve tissue in the forefoot.

Plantar Fasciitis (Heel Spur)

Heel pain from inflammation or irritation of the plantar fascia, often involving adjacent sensory nerves.

Ready to Feel Relief?

Explore the individual conditions listed above or book a consultation today to discuss whether cryoneurolysis is right for you.

Why Patients Choose Barcelona Cryo Center

  • Minimally Invasive

    Cryoneurolysis requires only a small skin puncture. No incision or general anesthesia is needed, which means minimal tissue impact and faster recovery.
  • Outpatient Care

    The treatment is completed during a single clinic visit. Patients come in, receive care, and return home the same day without hospital admission.
  • Ultrasound Guided

    Real-time imaging ensures precise placement next to the target nerve and improves both safety and effectiveness.
  • Evidence-Based Relief

    Clinical studies show that Cryoneurolysis can provide lasting relief from chronic pain while reducing the need for ongoing medication.
  • Specialized Pain Center

    Barcelona Cryo Center focuses exclusively on chronic pain, post-surgical pain, and spastic paresis related to conditions.
  • Unique In Barcelona

    Founded in Denmark in 2014, now in Barcelona offering ultrasound guided Cryoneurolysis, as well as advanced treatments for spasticity.
  • Opioid-Free Approach

    We treat chronic pain without using opioids such as morphine or related drugs.
  • Quality Of Life Focus

    Our goal is to help people with chronic or acute pain and spastic paresis live with less pain and greater independence.

Coverage

Prices in EUR
Consultation €100
Ultrasound-guided diagnostic block €250
Cryoneurolysis treatment for pain €1,500
Hyaluron injection – consultation + injection package €400
PRP – 3 treatment sessions €930

What to Expect

1

Free Records Review

We review your medical history to see if our approach is a good fit for your condition

2

Consultation

Patients who are a good fit for treatment will meet in person to further discuss

3

Treatment

Ultrasound-guided Cryoneurolysis, minimally invasive

4

Relief

Improved mobility and quality of life; plan for next steps

Meet Your Care Team

Real clinicians, modern methods, and a patient-first approach.

Igor Filipovski

Specialist in anesthesiology

Ognen Poposki

Specialist in Rehabilitation and Pain

Sonja Zikova

Administration and Finance Manager

Frequently Asked Questions

Click to open

Generally considered safe with trained clinicians; side effects can include temporary numbness, bruising, soreness.

Varies by condition; some patients have relief for months; plans can be revisited.

Coverage varies and is discussed at the consultation.

Ready to Take the Next Step?

Share a brief description of what you are looking for and we will follow up to schedule your consultation.
Please do not include medical history or sensitive personal information.

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Clinic Information

Address:
Pg. de la Bonanova, 91, Sarrià-Sant Gervasi, 08017 Barcelona

Phone: +34647915544

Monday: 16:00 to 20:00
Tuesday: 16:00 to 20:00
Wednesday: Closed
Thursday: 16:00 to 20:00
Friday: 16:00 to 20:00

Saturday and Sunday: By appointment