Chronic / Postoperative Knee Pain
Targeted Cryoneurolysis for Persistent Knee Pain After Injury or Surgery
What Is It?
Persistent knee pain following surgery, trauma, or arthritis can result from overactive or damaged sensory nerves within the knee joint. Even after a successful knee replacement or arthroscopic procedure, many patients report lingering pain that limits their mobility, activity level, and quality of life.
In many cases, this pain is not caused by joint instability or mechanical failure — but rather by irritation or entrapment of the genicular nerves, which transmit pain from the knee to the brain.
Common symptoms include:
- Persistent knee pain long after recovery from surgery or injury
- Aching or burning pain with standing, walking, or climbing stairs
- Tenderness around the front, side, or back of the knee
- Increased sensitivity to pressure or temperature
- Limited mobility due to pain, even with good joint healing
Common Causes
Cryoneurolysis may benefit knee pain resulting from:
- Total knee replacement (TKR) or revision procedures
- Post-arthroscopy or ligament repair surgery
- Genicular nerve irritation or entrapment
- Chronic inflammation or arthritis-related nerve sensitization
- Residual pain with no clear structural cause
How Cryoneurolysis Helps
Barcelona Cryo Center performs ultrasound-guided cryoneurolysis to treat the genicular nerves — the primary sensory nerves responsible for knee pain. By applying precisely controlled cold therapy, these nerves are temporarily deactivated, stopping abnormal pain signals while preserving strength and joint function.
This approach is especially valuable for patients who have already tried medications, injections, or even surgery without sustained relief. Cryoneurolysis can also be performed while patients are waiting for surgery, providing meaningful pain relief and improved quality of life during the preoperative period.
Key Benefits:
- Minimally invasive: No incisions or general anesthesia
- Outpatient procedure: Done in the clinic with minimal downtime
- Safe and repeatable: Relief may last several months per treatment
- Joint-preserving: Targets nerves without affecting joint mechanics
- Drug-free option: Reduces reliance on opioids or NSAIDs
Ideal Candidates
You may be a candidate for cryoneurolysis if you:
- Have ongoing pain after knee surgery or injury
- Experience sharp, aching, or burning pain around the knee
- Have exhausted other conservative treatments
- Want a nonsurgical, precision-based approach to relief
Step Toward Comfort and Mobility
Chronic knee pain can keep you from walking, working, and living the life you want. Cryoneurolysis offers a safe, targeted solution — helping you move with greater ease and less pain.
Book your consultation with Barcelona Cryo Center today.
Lower Extremity Conditions We Treat
We use cryoneurolysis to help patients manage a range of nerve-related pain conditions in the lower limbs:
Coverage
| Prices in EUR | |
|---|---|
| Consultation | €100 |
| Ultrasound-guided diagnostic block | €250 |
| Cryoneurolysis treatment for pain | €1,500 |
| Hyaluron injection – consultation + injection package | €400 |
| PRP – 3 treatment sessions | €930 |
Meet Your Care Team
Real clinicians, modern methods, and a patient-first approach.

Igor Filipovski
Specialist in anesthesiology

Ognen Poposki
Specialist in Rehabilitation and Pain

Sonja Zikova
Administration and Finance Manager
Frequently Asked Questions
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Clinic Information
Address:
Pg. de la Bonanova, 91, Sarrià-Sant Gervasi, 08017 Barcelona
Phone: +34647915544
Monday: 16:00 to 20:00
Tuesday: 16:00 to 20:00
Wednesday: Closed
Thursday: 16:00 to 20:00
Friday: 16:00 to 20:00
Saturday and Sunday: By appointment